Elucidating fundamental principles that govern viral entry, fusion, pathogenicity and restriction


We Have Three Major Research Areas:

Virus-cell and cell-cell fusion

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The entry of enveloped viruses, such as influenza A, HIV-1, SARS-CoV, and Ebola virus and others, utilize viral glycoproteins on its surface to mediate cellular attachment, tropism, and viral-host membrane fusion. 

Anti-viral immune restriction factors

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The human innate immune system has developed complex responses to prevent the spread of pathogens.

Discovery of anti-viral agents

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Using our structural models as a molecular blueprint, we aim to develop new therapeutic strategies to combat viruses.Understanding the entry, and immunological restriction of viral pathogens is fundamental for fighting infectious disease.

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Our Team