Elucidating fundamental principles that govern membrane fusion to understand fundamental biological processes
We Have Two Major Research Areas:
Virus-cell fusion
The entry of enveloped viruses, such as influenza A, HIV-1, SARS-CoV, and Ebola virus and others, utilize viral glycoproteins on its surface to mediate cellular attachment, tropism, and viral-host membrane fusion.
Cell-cell fusion
The fusion of membranes is also important in many biological processes, such as fertilization (sperm-egg fusion), placenta development (trophoblast fusion), skeletal muscle development (myoblast fusion), bone development (osteoclast fusion), among other processes.
